15N-ammonia absorption by the everted intestinal sac from conventional and germfree rats.

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An Investigation into the Role of P-Glycoprotein in the Intestinal Absorption of Repaglinide: Assessed by Everted Gut Sac and Caco-2 Cell Line

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An Investigation into the Role of P-Glycoprotein in the Intestinal Absorption of Repaglinide: Assessed by Everted Gut Sac and Caco-2 Cell Line

The present study aimed at exploring the potential of the P-glycoprotein (P-gp) transporters as a barrier to the repaglinide (REG) epithelial permeability. In-vitro intestinal absorption models, the everted gut sac, and Caco-2 cell line, were used to study the possible role of P-gp in intestinal transport of REG. In the everted gut sacs, apparent permeability coefficients showed cargo concentra...

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ژورنال

عنوان ژورنال: Nippon Eiyo Shokuryo Gakkaishi

سال: 1985

ISSN: 1883-2849,0287-3516

DOI: 10.4327/jsnfs.38.469